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Long lived BSA Au clusters as a time gated intensity imaging probe

Raut SL, Fudala R, Rich R, Kokate RA, Chib R, Gryczynski Z, Gryczynski I.

Nanoscale. 2014 ;6(5):2594-7.

Center for Commercialization of Fluorescence Technologies, Department of Cell Biology and Immunology, University of North Texas Health Science Center, 3500 Camp Bowie Blvd., Fort Worth, Texas 76107, USA. [email protected] [email protected]

Abstract

The work presented here reports the use of long lifetime (>1 us) BSA Au clusters as a cellular/tissue, time gated, intensity imaging probe. By collecting the emission signal 50 ns post excitation, one can off-gate the intense auto-fluorescence background, thereby greatly enhancing the clarity/specificity in fluorescence imaging.

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Long lived BSA Au clusters as a time gated intensity imaging probe.