Serine hydrolase inhibitors block necrotic cell death by preventing calcium overload of the mitochondria and permeability transition pore formation June 17, 2014 Read More »
Effect of molecular characteristics on cellular uptake, subcellular localization, and phototoxicity of Zn(II) N-alkylpyridylporphyrins. June 12, 2014 Ezzeddine R, Al-Banaw A, Tovmasyan A, Craik JD, Batinic-Haberle I, Benov LT. J Biol Chem. 2013, Dec 20;288(51):36579-88. Read More »
Endothelin receptor antagonist exacerbates autoimmune myocarditis in mice. June 7, 2014 Tajiri K, Sakai S, Kimura T, Machino-Ohtsuka T, Murakoshi N, Xu D, Wang Z, Sato A, Miyauchi T, Aonuma K. Life Sci. 2014 Jan 18. pii: S0024-3205(14)00070-8. Read More »
DropArray™, a wall-less 96-well plate for uptake and immunofluorescence microscopy, confirms CD22 recycles. June 7, 2014 Ingle GS, Scales SJ. Traffic. 2014 Mar;15(3):255-72. Read More »
Fluorescence linked enzyme chemoproteomic strategy for discovery of a potent and selective DAPK1 and ZIPK inhibitor. June 6, 2014 Carlson DA, Franke AS, Weitzel DH, Speer BL, Hughes PF, Hagerty L, Fortner CN, Veal JM, Barta TE, Zieba BJ, Somlyo AV, Sutherland C, Deng JT,Walsh MP, MacDonald JA, Haystead TA. ACS Chem Biol. 2013 Dec 20;8(12):2715-23. Read More »
Heat shock protein 90-{Alpha} mediates aldo-keto reductase 1B10 (AKR1B10) protein secretion through secretory lysosomes. June 2, 2014 Read More »
Pre-mRNA splicing-modulatory pharmacophores: the total synthesis of herboxidiene, a pladienolide-herboxidiene hybrid analog and related derivatives. June 2, 2014 Lagisetti C, Yermolina MV, Sharma LK, Palacios G, Prigaro BJ, Webb TR. ACS Chem Biol. 2014 Mar 21;9(3):643-8. Read More »
Total synthesis and anti-hepatitis C virus activity of MA026. May 28, 2014 Shimura S, Ishima M, Nakajima S, Fujii T, Himeno N, Ikeda K, Izaguirre-Carbonell J, Murata H, Takeuchi T, Kamisuki S, Suzuki T, Kuramochi K, Watashi K, Kobayashi S, Sugawara F. J Am Chem Soc. 2013 Dec 18;135(50):18949-56. Read More »
Baclofen, a GABAB receptor agonist, enhances ubiquitin-proteasome system functioning and neuronal survival in Huntington’s disease model mice. May 16, 2014 Kim W, Seo H. Biochem Biophys Res Commun. 2014 Jan 10;443(2):706-11. Read More »
Novel membrane bound reporter molecule for sorting high producer cells by flow cytometry May 16, 2014 Read More »
Carbamazepine suppresses calpain-mediated autophagy impairment after ischemia/reperfusion in mouse livers May 16, 2014 Read More »
Biosynthesis and expression of ADAMTS15 : a novel versican-cleaving proteoglycanase May 13, 2014 Read More »
The Dominant Role of IL-8 as an Angiogenic Driver in a Three-Dimensional Physiological Tumor Construct for Drug Testing. May 13, 2014 Read More »
Identification of BP16 as a non-toxic cell-penetrating peptide with highly efficient drug delivery properties. May 13, 2014 Soler M, González-Bártulos M, Soriano-Castell D, Ribas X, Costas M, Tebar F, Massaguer A, Feliu L, Planas M. Org Biomol Chem. 2014 Mar 14;12(10):1652-63. Read More »
Mechanism and Function of Monoclonal Antibodies Targeting Siglec-15 for Therapeutic Inhibition of Osteoclastic Bone Resorption May 8, 2014 Read More »
Halofuginone-induced amino acid starvation regulates Stat3-dependent Th17 effector function and reduces established autoimmune inflammation May 8, 2014 Carlson TJ, Pellerin A, Djuretic IM, Trivigno C, Koralov SB, Rao A, Sundrud MS. J Immuol. 2014 Mar 1;192(5):2167-76. Read More »
Protein profiles associated with context fear conditioning and their modulation by memantine May 8, 2014 Read More »
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