Probing o-diphenylphosphanyl benzoate (o-DPPB)-directed C-C bond formation: total synthesis of dictyostatin May 8, 2015 Read More »
Coupling to a glioblastoma-directed antibody potentiates antitumor activity of curcumin May 2, 2015 Read More »
Computer aided drug discovery of highly ligand efficient, low molecular weight imidazopyridine analogs as FLT3 inhibitors April 24, 2015 Read More »
Disulfiram-induced cytotoxicity and endo-lysosomal sequestration of zinc in breast cancer cells. April 24, 2015 Read More »
Alisporivir inhibition of hepatocyte cyclophilins reduces HBV replication and hepatitis B surface antigen production April 24, 2015 Read More »
Discovery of amphipathic dynorphin A analogues to inhibit the neuroexcitatory effects of dynorphin A through bradykinin receptors in the spinal cord April 24, 2015 Read More »
Activated α2-Macroglobulin Binding to Human Prostate Cancer Cells Triggers Insulin-like Responses. April 24, 2015 Misra UK1, Pizzo SV2. J Biol Chem. 2015 Apr 10;290(15):9571-87. Read More »
Trabectedin Efficacy in Ewing Sarcoma Is Greatly Increased by Combination with Anti-IGF Signaling Agents. April 18, 2015 Read More »
A novel class of ruthenium-based photosensitizers effectively kills in vitro cancer cells and in vivo tumors April 18, 2015 Read More »
Prolyl Oligopeptidase Enhances α-Synuclein Dimerization via Direct Protein-Protein Interaction April 11, 2015 Read More »
A functional approach reveals a genetic and physical interaction between ribonucleotide reductase and CHK1 in mammalian cells April 11, 2015 Taricani L, Shanahan F, Malinao MC, Beaumont M, Parry D. PLoS One. 2014 Nov 6;9(11):e111714. Read More »
Sarcoplasmic reticulum Ca(2+) ATPase pump is a major regulator of glucose transport in the healthy and diabetic heart April 11, 2015 Read More »
Tocotrienol preserves ovarian function in cyclophosphamide therapy. March 31, 2015 Saleh H1, Omar E2, Froemming G3, Said R4. Hum Exp Toxicol. 2015 Jan 13. pii: 0960327114564793. Read More »
The potent Cdc7-Dbf4 (DDK) kinase inhibitor XL413 has limited activity in many cancer cell lines and discovery of potential new DDK inhibitor scaffolds March 31, 2015 Read More »
Targeting Three Distinct HER2 Domains with a Recombinant Antibody Mixture Overcomes Trastuzumab Resistance March 23, 2015 Pedersen MW1, Jacobsen HJ2, Koefoed K2, Dahlman A2, Kjær I2, Poulsen TT2, Meijer PJ2, Nielsen LS2, Horak ID2, Lantto J2, Kragh M2. Mol Cancer Ther. 2015 Jan 22. Read More »
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