Umbilical cord blood-derived mesenchymal stem cells inhibit, but adipose tissue-derived mesenchymal stem cells promote, glioblastoma multiforme proliferation. October 28, 2013 Akimoto K, Kimura K, Nagano M, Takano S, To’a Salazar G, Yamashita T, Ohneda O. Stem Cells Dev. 2013 May 1;22(9):1370-86 Read More »
Opposing actions of sevoflurane on GABAergic and glycinergic synaptic inhibition in the spinal ventral horn October 22, 2013 Eckle VS, Hauser S, Drexler B, Antkowiak B, Grasshoff C. PLoS One. 2013;8(4):e60286. Read More »
MicroRNAs 185, 96, and 223 repress selective high-density lipoprotein cholesterol uptake through post-transcriptional inhibition October 8, 2013 Read More »
Salvianolic acid A, a novel matrix metalloproteinase-9 inhibitor, prevents cardiac remodeling in spontaneously hypertensive rats September 3, 2013 Read More »
X-ray structures of two forms of the antibiotic oligomycin A: an inhibitor of ATP synthase. August 21, 2013 Palmer RA, Ladd M, Howlin B, Lisgarten DR. Future Med Chem. 2013 May;5(8):881-93. Read More »
Gentamicin binds to the megalin receptor as a competitive inhibitor using the common ligand binding motif of complement type repeats August 21, 2013 Read More »
Tripolin A, a novel small-molecule inhibitor of aurora A kinase, reveals new regulation of HURP’s distribution on microtubules. July 4, 2013 Read More »
Extra-cell cycle regulatory functions of cyclin-dependent kinases (CDK) and CDK inhibitor proteins contribute to brain development and neurological disorders. June 4, 2013 Read More »
Tempol moderately extends survival in a hSOD1(G93A) ALS rat model by inhibiting neuronal cell loss, oxidative damage and levels of non-native hSOD1(G93A) forms. May 8, 2013 Read More »
5-Aminosalicylic acid inhibits cell cycle progression in a phospholipase D dependent manner in colorectal cancer. April 18, 2013 Baan B, Dihal AA, Hoff E, Bos CL, Voorneveld PW, Koelink PJ, Wildenberg ME, Muncan V, Heijmans J, Verspaget HW, Richel DJ, Hardwick JC, Hommes DW,Peppelenbosch MP, van den Brink GR. Gut. 2012 Dec;61(12):1708-15. Read More »
Human anti-varicella-zoster virus (VZV) recombinant monoclonal antibody produced after Zostavax immunization recognizes the gH/gL complex and neutralizes VZV infection April 13, 2013 Read More »
The HSP90 inhibitor geldanamycin perturbs endosomal structure and drives recycling ErbB2 and transferrin to modified MVBs/lysosomal compartments. April 13, 2013 Cortese K, Howes MT, Lundmark R, Tagliatti E, Bagnato P, Petrelli A, Bono M, McMahon HT, Parton RG, Tacchetti C. Mol Biol Cell. 2013 Jan;24(2):129-44. Read More »
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