Mechanisms of acquired resistance to insulin-like growth factor 1 receptor inhibitor in MCF-7 breast cancer cell line. February 9, 2014 Ekyalongo RC, Mukohara T, Kataoka Y, Funakoshi Y, Tomioka H, Kiyota N, Fujiwara Y, Minami H. Invest New Drugs. 2013;31(2):293-303. Read More »
Potassium channel activation inhibits proliferation of breast cancer cells by activating a senescence program. February 4, 2014 Lansu K, Gentile S. Cell Death Dis. 2013;4:e652. Read More »
Activity, inhibition, and induction of cytochrome P450 2J2 in adult human primary cardiomyocytes. January 29, 2014 Evangelista EA, Kaspera R, Mokadam NA, Jones JP 3rd, Totah RA. Drug Metab Dispos. 2013 Dec;41(12):2087-94. Read More »
Pharmacokinetics of the amidine prodrug of a novel oral anticoagulant factor VIIa inhibitor (AS1924269-00) in rats. December 25, 2013 Nakabayashi T, Gotoh Y, Kamada N, Fujioka M, Ishihara T, Hirabayashi A, Sato H. Pharmazie. 2013 May;68(5):349-54. Read More »
Tagging of genomic STAT3 and STAT1 with fluorescent proteins and insertion of a luciferase reporter in the cyclinD1 gene provides a modified A549 cell line to screen for selective STAT3 inhibitors. December 18, 2013 Samsonov A, Zenser N, Zhang F, Zhang H, Fetter J, Malkov D. PLoS One. 2013 Jul 9;8(7):e68391. Read More »
The anti-inflammatory compound BAY-11-7082 is a potent inhibitor of protein tyrosine phosphatases. December 10, 2013 Krishnan N, Bencze G, Cohen P, Tonks NK. FEBS J. 2013 Jun;280(12):2830-41. Read More »
Androgen metabolite-dependent growth of hormone receptor-positive breast cancer as a possible aromatase inhibitor-resistance mechanism. December 10, 2013 Hanamura T, Niwa T, Nishikawa S, Konno H, Gohno T, Tazawa C, Kobayashi Y, Kurosumi M, Takei H, Yamaguchi Y, Ito K, Hayashi S. Breast Cancer Res Treat. 2013 Jun;139(3):731-40. Read More »
Inhibition of intracellular dipeptidyl peptidases 8 and 9 enhances parthenolide’s anti-leukemic activity. December 4, 2013 Spagnuolo PA, Hurren R, Gronda M, MacLean N, Datti A, Basheer A, Lin FH, Wang X, Wrana J, Schimmer AD. Leukemia. 2013 Jun;27(6):1236-44. Read More »
The inhibition of human tumor cell proliferation by RNase Pol, a member of the RNase T1 family, from Pleurotus ostreatus. December 4, 2013 Kobayashi H, Motoyoshi N, Itagaki T, Tabata K, Suzuki T, Inokuchi N. Biosci Biotechnol Biochem. 2013;77(7):1486-91. Read More »
Comprehensive analysis of varicella-zoster virus proteins using a new monoclonal antibody collection. December 4, 2013 Lenac Rovis T, Bailer SM, Pothineni VR, Ouwendijk WJ, Simić H, Babić M, Miklić K, Malić S, Verweij MC, Baiker A, Gonzalez O, von Brunn A, Zimmer R, Früh K,Verjans GM, Jonjić S, Haas J. J Virol. 2013 Jun;87(12):6943-54. Read More »
Bioactive secondary metabolites of a marine Bacillus sp. inhibit superoxide generation and elastase release in human neutrophils by blocking formyl peptide receptor 1. November 27, 2013 Yang SC, Lin CF, Chang WY, Kuo J, Huang YT, Chung PJ, Hwang TL. Molecules. 2013 Jun 3;18(6):6455-68. Read More »
The novel Chk1 inhibitor MK-8776 sensitizes human leukemia cells to HDAC inhibitors by targeting the intra-S checkpoint and DNA replication and repair. November 27, 2013 Dai Y, Chen S, Kmieciak M, Zhou L, Lin H, Pei XY, Grant S. Mol Cancer Ther. 2013 Jun;12(6):878-89. Read More »
Cisplatin-induced cell death in Saccharomyces cerevisiae is programmed and rescued by proteasome inhibition. November 20, 2013 Cunha D, Cunha R, Côrte-Real M, Chaves SR. DNA Repair (Amst). 2013 Jun 1;12(6):444-9. Read More »
A2B adenosine receptor blockade inhibits growth of prostate cancer cells November 16, 2013 Wei Q, Costanzi S, Balasubramanian R, Gao ZG, Jacobson KA. Purinergic Signal. 2013 Jun;9(2):271-80. Read More »
Cluster-based molecular docking study for in silico identification of novel 6-fluoroquinolones as potential inhibitors against Mycobacterium tuberculosis November 16, 2013 Minovski N, Perdih A, Novic M, Solmajer T. J Comput Chem. 2013 Apr 5;34(9):790-801. Read More »
Concanavalin-A induces granulosa cell death and inhibits FSH-mediated follicular growth and ovarian maturation in female rats November 12, 2013 Read More »
A thiocarbamate inhibitor of endothelial lipase raises HDL cholesterol levels in mice. November 7, 2013 Greco MN, Connelly MA, Leo GC, Olson MW, Powell E, Huang Z, Hawkins M, Smith C, Schalk-Hihi C, Darrow AL, Xin H, Lang W, Damiano BP, Hlasta DJ. Bioorg Med Chem Lett. 2013 May 1;23(9):2595-7. Read More »
Methadone but not morphine inhibits lubiprostone-stimulated Cl- currents in T84 intestinal cells and recombinant human ClC-2, but not CFTR Cl- currents. November 2, 2013 Cuppoletti J, Chakrabarti J, Tewari K, Malinowska DH. Cell Biochem Biophys. 2013 May;66(1):53-63. Read More »
Valproic acid attenuates ischemia-reperfusion injury in the rat brain through inhibition of oxidative stress and inflammation November 2, 2013 Suda S, Katsura K, Kanamaru T, Saito M, Katayama Y. Eur J Pharmacol. 2013 May 5;707(1-3):26-31. Read More »
Lapatinib inhibits meiotic maturation of porcine oocyte-cumulus complexes cultured in vitro in gonadotropin-supplemented medium. November 2, 2013 Read More »
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